Tuesday, 31 January 2017

Female infertility treatment in Chennai

Pregnancy Care and Treatments

GOAL OF ANTENATAL CARE – HAPPY & HEALTHY MOTHER AND BABY

Pregnancy is divided into 3 trimesters for our convenience

1st trimester
2nd trimester
3rd trimester
Formation of Fetus
Growth of Fetus
Maturity around 37 weeks and preparatory stage for delivery



Female infertility treatment in Chennai

Fig 1.1 Pregnancy Care and Treatments 

FIRST TRIMESTER (Formation of Fetus) : - 1,2,3 months of pregnancy

History taking:



1)    Age

2)    Married life

3)    LMP : EDD

4)    CONSANGUINEOUS / NON-CONSANGUINEOUS

5)    History of previous pregnancies

6)   Any medicines using for Diabetes, Hypertensions, Hypothyroidism, Epilepsy,
          Asthma or Psychiatric problems.

7)   Family History of Diabetes, Hypertension, Twins, Anomaly babies.

8)   Weight, BP, look for Anemia and swelling of feet.

  Routine investigations:- 

   HB%, Blood group, Urine Micro, RBS, T4, TSHScreening tests – HBsag,  Tridot,HCV, VDRL

       Scan:- 
     
           a) Dating Scan:- To the site of pregnancy, Gestational age, Viability fetus.
         
           b) NT Scan (11-13 weeks):- To rule out down’s Syndrome.
     
       Double Marker Test:- 
     
          Done in patients aged > 35years & in all precious pregnancies to rule out down’s           syndrome
     
       AVOID:-  
            
           Sexual contact, Spicy food, Weight lifting, Journeys.

       MEDICINES:-  

           Folic Acid, B12 (B-complex)
     

Female infertility treatment in Chennai
Fig 1.2 First Trimester during pregnancy 


  Any other drugs should be used only with Doctor’s Advice (Prescription).

SECOND TRIMESTERS (GROWTH OF FETUS):- 4,5,6 Months of pregnancy

Routine Examination:-  Weight, BP, Height of Uterus, Fetal heart rate (Doppler)

Tests:-
  • HB%, RBS/PPBS/GCT, Urine Micro          
  • Any infection in Urine à Advise to take more liquids and frequent voiding of Urine, keep nails cut.
  • Repeated infection in urine à Urine culture/Sensitivity and add Antibiotics. White Discharge:- Anti Fungal, Anti Micro bials if warranted.


Female infertility treatment in Chennai

Fig 1.3 Second Trimisters during pregnancy 


Scan:-

TIFFA SCAN(Targeted imaging for fetal anomalies) at 20 to 24 weeks

 Most of the anomalies can be identified during TIFFA Scan.

Limitation of Ultra Sono Graphy

1.     Some anomalies develop late in pregnancy

2.  Some of the anomalies like Gastrointestinal tract anomalies,Multiple Cardiac anomalies are difficult to identify

3.  Only structural anomalies can be identified, functional anomalies like speech,  hearing, vision can be identified only after birth.


Female infertility treatment in Chennai

Fig 1.4 Scan At pregnancy 


MEDICINES:

1.     Iron tablets from 4th month -  To prevent Anemia

2.     Calcium tables from 5th month – To strengthen bones and teeth of baby

3.     DHA (Omega-3 fatty acids) from 7th month – To improve IQ of baby.

Infertility doctor in Chennai

Fig 1.5  Medicine to be followed in pregnancy 


ALL THREE MEDICINES CAN BE CONTINUED AFTER DELIVERY.

EXERCISES:

1.     Walking.
2.     Breathing exercises.
3.     Household work.


THIRD TRIMESTER (Maturity of fetus around 37 weeks preparatory stage for delivery):- 7, 8, 9 Months of pregnancy.

CHECK UP:
  • Till 7th month à Monthly Checkup
  • 8th month        à Once in 2 weeks checkup
  • 9th month        à Weekly once checkup


v Normal weight gain is 2kg/month

v If more than 2kg weight gain à look for fluid retention in body seen as swellingof feet, face, abdomen, hands etc.

Infertility doctor in Chennai

Fig 1.6 Trimesters of pregnancy 

    
  i) Mainly pregnancy induced hypertension, Anemia, Hypoprotenaemia                                                    
  ii) Rarely Cardiac, Renal causes.


INCASE OF PREGNANCY INDUCED HYPERTENSION/PREECLAMPSIA

1.     Patient should come for frequent checkup and should be under close monitoring to prevent ECLAMPSIA.

2.  To report immediately if there are any imminent symptoms of Eclampsia like            headache, blurred vision, Epigastric pain(vomiting), decreased urine output,              increased pedal edema.

3.     Advise à Diet, Rest and treatment.

SCANS:-

Growth Scan – 8th Month
9th Month Scan – 37 weeks.

Emergency visits to hospital in 9th Month

Leaking, Bleeding, Fever, Pain Abdomen, Decreased Fetal Movements

TESTS:-

  • HB%, RBS/PPBS/GCT, Urine Micro
  • At 35 weeks à BT, CT, Platelet count, Serum Creatinine, Serum Bilirubin


DIET DURING PREGNANCY

Diet during pregnancy should be adequate to provide
1.     Good Maternal Health
2.     Optimum Fetal growth
3.     Strength and vitality during labour
4.     Successful lactation


Fig 1.7 Diet and Healthy food During Pregnancy 


IRON (40mg/day):-

·     Increases oxygen carrying capacity in blood, prevents – weakness infections Increases pain bearing capacity, improves lactation in mothers, Decreases premature labour and low birth weight of the baby.

1.     Heme iron 

à Animal Sources
à Red meat, egg, fish

2.     Non Heme Iron 

à Vegetable source
à Green Leafy vegetables, Spinach, beans, peas, carrot,beetroot, tomato, potato, broccoli, lentils.
à FRUITS: Straw berry, Apple, Pear, Peach, Plums.
à IRON BOOSTING FRUITS: Citrus, Melons, Guava
à DRY FRUITS: Dates, Figs, Raisins
à SEEDS: Almond, Cashew, Sunflower seeds, Pumpkin seeds, Jaggery,
            Using iron utensils for cooking.

Infertility Specialist in Chennai

CALCIUM: (1000mg/day): 


  • Helps in building bones and teeth of baby

Sources: 

Milk 300mg, Yogurt – 370mg, Cheese, Sesame seeds – 200mg,Spinach – 250mg, Cabbage, Cauliflower, Broccoli, Orange – 60mg, Date – 15mg, Almonds, Figs, Raisins.
                                 


Calcium Absorption:


  • Increased by Vitamin D and Magnesium.
  • Decreased by salt, Coffee, Alcohol,
  • Phytates (nuts and grains) and oxalates in spinach

PROTEIN (60grams/day): 


  • Building block of tissues

Milk – 8gm, Curd – 10gm, Cheese – 14gm, Lentil 1 cup – 15gm, Beans 1 cup – 18gm, Nuts and seeds, Egg – 6gm, Chicken – 27gm, Fish – 23gm.


Fig 1.8 Protein During Pregnancy

FOLIC ACID(400 Micrograms/day):

Prevents:

1.     Neural tube defect
2.     Down’s Syndrome
3.     Recurrent abortions
4.     Preeclampsia
5.     Low birth weight

Sources:-


  • Lentils, Spinach and Orange.

OMEGA – 3 Fatty acids (DHA 300mg)

Fetus:-

1.     Brain and Eye development
2.     Decrease low birth weight
3.     Decrease allergy and eczema

Mother:- 


  • Decrease pre-eclamptic toxemia, Depression

Sources:- 


  • Flax Seeds, Walnuts, Cold water fatty fish (Salmons, Sardine, Cod fish,   HALIBUT)





Friday, 27 January 2017

STORIES ABOUT FOLLICULAR STUDY AND IRREGULAR PERIODS



This is about lady  with 28 years married for 5 years with irregular periods. When we did follicular study follicles are not developing well. we increased the dosage of cloniphene  citrate from 50 to 200mg with added dosage of injection FSH. Still she had no proper growth of follicles. I felt it was a very difficult case. She was also dejected and stopped treatment. 


Fig 1.1 Irregular periods Days 


After one and half year she came again and I remembered her case; I thought again  the same problem might recur. But she was happy and smiling. She said  her periods had become  regular, she wanted to go for follicular study that cycle .


Fig 1.2 Irregular Period Time and Worries


she also suggested that I induce the cycle with 100mg  clome tablets as her periods have become regular. I was surprised but obliged her, as there was some reasoning in it. To my astonishment the follicles developed very nicely and ruptured at the optimum size of 20x23mm. Both of us were happy about it and she conceived  the same cycle. I asked how her periods became regular and she had this story to tell. 


Fig 1.3 Period Cycles and Treatments 


She was a joint family .she was unemployed previously  and  her husband had temporary job. To come to the clinic she had to ask her mother-in-law for medical expenses; her co sisters would be grumbling to adjust the household work whenever she came to the hospital. Coming to hospital was a big ordeal for her. The follicle problem made her feel helpless and hopeless. 



Fig 1.4 Normal Ovary and Polycystic ovaries comparison 


Six months after stopping the treatment her husband got a permanent job and they setup a separate family; she also started doing a job. There was a financial freedom and no quarreling with co sisters. She was peaceful and happy. She was busy doing household work and office work there was no time to think and worry about pregnancy. She was surprised to find her periods becoming regular for the past 6 months. After observing the regularity of the periods, she felt that her periods improved and felt confident about herself and decided to take treatment. This story made me understand that influence of emotions on follicle growth.


Fig 1.5  Heavy Pain During Periods



         Women was married for 10years with history of irregular periods and pco. She had already undergone  laparoscopy elsewhere for pco and unfortunately her problem had recurred. She was not obese; I had given her medicines and did follicular study there was no follicular growth. Women  volunteered to undergo laparoscopy with me. She was very firm about the decision. So I did repeat ovarian drilling ; after the surgery also ,though the pco was cleared the periods was irregular and there was no improvement in follicle growth.


Fig 1.6 Treatments for Ovaries 


The surprising observation about her was that she never felt dejected or cried. It seemed  that she has accepted the irregular periods. She was very cool and talked normally. She never felt bad about the improper follicular growth,      in contrast to other prospective mothers with same problem, who used to feel anxious and worried about follicular problem.

 I asked about her (adamant and persistent) irregular periods, when it started and other details and she narrated her story. She used to have regular periods since menarche (the time of attaining maturity). A few months before her marriage she developed heavy bleeding and her mother took her to a doctor, who prescribed hormone pills ( 3 weeks pills). 



Video 1.1 Andal Fertility Treatments for periods



She was advised to take the tablets for 3 months. She took the pills for 1 month  and the    next month she went  to her grandmothers place;  there she went to the medical shop and ask for the pill. The chemist who was their family friend told her, “ young  girls like you should not use these tablets; you have taken for 1 month! Don’t take it.” 

so she felt guilty that she had taken some dangerous pills that would have surely harmed her uterus. From then on her periods became irregular. I could see  her firm belief that uterus and ovary were damaged was the reason  for her irregular periods.

 I told her that we use such tablets some times for 6 months or more also depending on the necessity. Unmarried girls also can safely use those pills , under supervision for right indications. I convinced her if she believed my words backed with experienced ,she would surely get regular periods as her uterus and ovaries are as normal as anybody else. 

She  appeared relieved; and came after 3 weeks with periods without using any tablets. She was surprised and happy. I advised her strongly to indulge in some hobby. She started painting saries. her periods became consistently regular, with normal follicular study and she conceived. Now she is having 2 children.



Tuesday, 24 January 2017

FAMILY PLANNING METHODS AND TREATMENT TO BE FOLLOWED

The term contraception includes all  temporary or permanent measures, to prevent pregnancy .
         
Ideal contraceptive methods should fulfill the following criteria – widely acceptable, inexpensive, simple to use, safe, highly effective and requiring minimal motivation, maintenance and supervision.

      
Best infertility center in Chennai

Fig 1.1 Family Planning Methods and Treatments 


TEMPORARY:    
                                                            
BARRIERMETHODS
IUCD(INTRAUTERINE contraceptive device)
OCP(oral contraceptive pill)

PERMANENT

MALE ---Vasectomy 
FEMALE---Tubectomy

Infertility Specialist in Chennai


Fig 1.2 Temporary and permanent method  


BARRIER METHODS
·     
        Mechanical:

       1.  Male – Condom
       2. Female – Condom, diaphragm, cervical cap
           Chemical
        (Vaginal contraceptives)
       3. Creams – Delfen (nonoxynol-9, 12.5%)
       4. Jelly – Koromex, Volpar paste
       5. Foam tables – Aerosol foams, Chlorimin T or Contab, Sponge (Today)
           Combination
        
            Combined use of mechanical and chemical

Infertility Treatment in Chennai

Fig 1.3 Using Condom to Stop pregnant

CONDOM

ADVANTAGES
DISADVANTAGES

May accidentally break or slip off during coitus.

Inadequate sexual pleasure.
Easy to carry, simple to use and disposable.
To discard after one coital act.
Useful where the coital act is infrequent and irregular
Protection against sexually transmitted diseases, e.g. gonarrhoea, Chlamydia, HPV and HIV

Protection against pelvic inflammatory diseases


Failure rate – 14(HWY); 3(HWY) when used correctly and consistently.

Precautions:
  •   To use a fresh condom for every act of coitus.
  •   To cover the penis with condom prior to genital contact
  •   Create a reservoir at the tip.
  •   To withdraw while the penis is still erect.
  •   To grasp the base of the condom during withdrawal.


Infertility Treatment in Chennai

Fig 1.4 Methods to stop Female Pregnancy 


FEMALE CONDOM (FEMIDOM)
It gives protection against sexually transmitted disease and pelvic inflammatory disease. It is expensive. Failure rate is about 3-5/HWY.

VAGINAL CONTRACEPTIVES:
The cream or jelly is introduced high in the vagina . Foam tablets (1-2) are to be introduced high in the vagina at least 5 minutes prior to intercourse.


Infertility Treatment in Chennai

Fig 1.5 Safety measures to stop pregnancy and anticare

VAGINAL CONTRACEPTIVE SPONGE (Today)

It is made of polyurethane impregnated with 1gm of nonoxynol-9 as a spermicide. Nonoxynol-9 acts as a surfactant which either immobilizes or kills sperm. The sponge should not be removed for 6 hours after intercourse. It’s failure rate is about 10/HWY.


Male infertility treatment in Chennai

Fig 1.6 Vaginal Contraceptive Sponge  

RHYTHM METHOD:

This method is based on identification of the fertile period of a cycle and to abstain from sexual intercourse during that period.

The first unsafe day is obtained by subtracting 20 days from the length of the shortest cycle and last unsafe day by deducting 10 days from the longest cycle.

Failure rate 20-30 (HWY)
Not applicable during lactational amenorrhoea or when the periods are irregular


Male infertility treatment in Chennai

Fig 1.7 Rhythm Method to delay conceive

COITUS INTERRUPTUS:
It necessitates withdrawal of penis shortly before ejaculation. Accidental chance of sperm deposition into the vagina. Failure rate – 20(HWY)

Male infertility treatment in Chennai

Fig 1.9 Coitus Interupptus

BREASTFEEDING, LACTIONAL AMENORRHOEA (LAM)

Thus during breastfeeding, additional contraceptive support should be given by condom, IUCD or injectable steroids where available to provide complete contraception.

When the women is full breastfeeding, a contraceptive method should be used in the 3rd postpartum month  and with partial or no breastfeeding, she should use it in the 3rd postpartum week.

full breastfeeding   and amennorhoehic   - risk of pregnancy <2% in first 6 months
 general  ---  risk of pregnancy 1- 10%

                                          
Female infertility treatment in Chennai

Fig 1.10 Brestfeeding ,lactional amenorrhoea(LAM)

INTRAUTERINE CONTRACEPTIVE DEVICES(IUCD)

Cu T200B  ------ replaced every 3 years
Cu T 380A:- ----Replacement  every 10 years

Multiload Cu 250:- replacement  every 3 years. Multiload Cu375   replaced every 5 years
Levonorgestrel intrauterine system (LNG-IUS):- n replaced every 5 years.

Female infertility treatment in Chennai

Fig 1.11 Intrauterine Conceptive Devices

MODE OF ACTION:



Video 1.1 Fertility and Treatments 
  •          Biochemical and histological changes in the endometrium
  •          Copper devices – Preventing implantation through enzymatic interference.
  •          There may be increased tubal motility
  •          There may be impaired sperm ascent
  •          Levonorgestrel-IUS(Mirena) – It induces strong and uniform suppression of                   endometrium. 
  •          Cervical mucous becomes very scantly.
  •          I is preferable to insert 2-3 days after the period is over.

 CONTRA INDICATION   FOR IUCD INSERTION

1)MENORRHAGEA 

2)PELVIC INFECTION(PID) 

3)DYSMENORRHOEA

factors related to its discontinuation (10%-15%)
Pain, abnormal uterine bleeding and PID

SPONTANEOUS EXPULSION – The expulsion rate is about 5 percent.

FAILURE RATE– 

The pregnancy rate with the device in situ is about 2 per 100 women years of use. Lowest 

pregnancy rates are observed with Cu T 380A (0.8-HWY) and LNG-IUS (0.2 – HWY).


Best infertility center in Chennai

Fig 1.12 Contra indication for insertion 

  •     3rd generation IUCD(Cu T 380A, Multiload Cu375  and Levonorgestrel-IUS(Mirena)
  •     Higher efficacy with lowest pregnancy rate (less than one pre 100 women years).
  •     Longer duration of action (5-10 years)
  •     Low expulsion rate and fewer indications for medical removal.
  •     Risk of ectopic pregnancy is significantly reduced (Cu T-380A and LNG-       IUS:0.02HWY)
  •     Non-contraceptive benefits specially with LNG-IUD
  •     Can be used as an alternative to hysterectomy for menorrhagia, DUB.
  •     Apart from the use of Cu T as a contraceptive, it is used following synaecolysis.

OCP(ORAL CONTRACEPTIVE PILLS)   ----- NAMES


COMMERCIAL NAMES
                              COMPOSITION
No. of tablets
Progestin’s(mg)
Oestrogen (ug)
1.Mala N( Govt.of India)
Levonorgestreal 0.15
Ethinyl  oestradiaol 30
21+7 Iron tablets
2.Mala- D
Levonorgestreal 0.15
Do
21+7 Iron tablets
3.Femilon (Infar)

Desogestreal 0.15
Ethinyl  oestradiaol 20
21
4.Yasmin(Schering)
Drospirenone 3 mg (p.509)
Ethinyl  oestradiaol 30
21
Depending on the amount of ethinyl oestradiaol (E) and the types of progestin (p) used , pills are defines as: 1ST GENERATION – With E 50 UG or more ; 2nd  GENERATION --  with e 30- 35 ug and p as levonorgestrel or norgestimate ;  3rd GENERATION – WITH e 20- 30 ug and p as desogestrel or gestodene Low dose pills have E less than 50 ug. 

HOW TO PRESCRIBE A PILL:

New users should normally start their pill packet on day one of their cycle.

FOLLOW UP:  


After 3months,6 months and yearly check up necessary. The patient above the age 35 should be checked more frequently.

MISSED PILLS:

When she misses two pills in the first week (days 1-7), she should take 2 pills on each of the 
next 2 days and then continue the rest as schedule. Extra precaution has to be taken for next 7 days either by using a condom or by avoiding sex.

If 2 pills are missed in the third week (days 15-21) or if more than two active pills are missed at any time, another form of contraception should be used as back up for nest 7 days as mentioned above. She should start the next pack without a break.

If she misses any of the 7 inactive pills (in a 28day pack only) she should throw away the missed pills. She should take the remaining pills one a day and start the new pack as usual.
Indications for withdrawal : The indication for withdrawal  of the pill are 

Best infertility center in Chennai
                                               
                                                   Fig 1.13 Oral Contraceptive Pills 

1)serve migraine 
2) Visual or Speech disturbance 
3) Sudden chest pain 
4) Unexplained  fainting attack or acute vertigo 
5) Serve cramps and pain sin legs
6) Excessive weight gain 
7) Severe depression
8) Prior to surgery (it should be with held for at least 6 weeks to minimize postoperative           vascular complications). 
9) Patient wanting pregnancy.

pill be continued :

A Woman who does not smoke and has no other risk factor for cardiovascular disease , may continue the pill for 3 to 5 years is considered  enough and safe .

Failure rate:

 1)Protection against unwanted pregnancy (failure rate – 0.1 per 100 women year)
    Non contraceptive benefits  : Improvement of menstrual  abnormalities – 1) Improvement     of menstrual abnormalities
2) Reduction of dysmenorrhea  (40%)
3) Reduction of menorrhagia (50%) 
4) Reduction of premenstrual  tension syndrome (PMS) 
5) Reduction of Mittelschmerz’s  syndrome.
6) Protein against iron deficiency anemia .


 

Video 1.2 Treatments in Andal Fertility clinic

12) Functional  ovarian cysts 
13) benign breast disease
14) Osteopenia and postmenopausal  osteoporotic  fractures. Prevention of malignancies   Endometrial cancer (50%) 
18) Ovarian cancer (40%)
19) Colorectal cancer (40%)  This protective effects persists for 10 -15 years even after stopping the methods following a use of 6 months to 1 years .

SIIDE EFFECTS : 

NAUSEA, VOMITING ,HEADACHE (OGN) AND LEG CRAMPS (PGN) : These are transient and often subside following continuous use for 2-3 cycles .

WEIGHT GAIN: 

Though progestins have got an anabolic effects due to its chemical relation to testosterone, use of low dose COCs does not cause any increase in weight.


MENSTRUAL ABNORMALITIES -
·      
Breakthrough bleeding  is commonly due to sub threshold blood level of hormones

other causes of break through bleeding in pill takers are

                  1) disturbance of drug absorption – diarrhea , Vomiting
               
                  2)use of enzyme inducing drugs (mentioned earlier) , missing pills, use of low does                              pills
               
                  3) pregnancy complications
               
                  4) Diseases  -- cervical ectopy or carcinoma.
·      
Amenorrhea: 

Post pill amenorrhea of more than 6 months duration occurs in less than 1 percent cases. The association is casual not casual .it is usually more in women with per-existing functional menstrual disorders.


Hypertension: Current low dose COC5 rarely cause significant hypertension. Pre-existing Hypertension  is likely to be aggravated.

Best infertility treatment in Chennai

Fig 1.14 Oral Natural Abnormalities 

VASCULAR COMPLICATIONS (OGN): 


Venous thromboembolism (vtm)  - the overall risk is to the extent of 4-6 times more than the non –users .pre-existing hypertension, diabetes , obesity and elderly patient (over 35 specially with smoking habits ) are some of the important risk factors ethinyl  oestrodiol in preference to menstranol and the reduction of the dose of the oestrogen compound to 20 ug in the pill markedly reduce the incidence


LIPID (OGN): 


Plasma lipids and lipoproteins are increased .total cholesterol and triglycerides are increased .Preparation with more selective, lipid friendly and third generation progestin’s namely desogestrel, gestodeone or norgestimate, HDL Level is some what elevated .

VITAMINS AND MINERALS: 

Vitamins b6,b12, folic acid ,calcium , manganese, zinc and ascorbic acid levels are decreased  while vit a and vit k levels are increased.

INJECTABLE PROGESTINS: 

NET –EN IN A DOSE OF 200 MG GIVEN AT TWO – MONTHLY INTERVELS.DMPA 150 mg three monthly intervals. 

Mechanism of action :

1) Inhibition of ovulation by suppressing the mid cycle LH Peak 

2) cervical mucous becomes thick and viscid therapy prevents sperm penetration 

3) Endometrium is atrophic preventing blastocyst implantation


Fig 1.14.a. Ingectible Progestins 


Advantages :

 1)it eliminates regular medication as imposed by oral pill

 2) it can be used safely during lactation.

Disadvantages :


There is chance of irregular bleeding and occasional phase of amenorrhea. Loss of bone 

mineral density has been observed with along term use of depot provera.

OTHER EFFECTS : 

Weight gain and Headache

EMERGENCY CONTRACEPTION

·         Hormones
·         IUD
·         ANTIPROGESTRONE
·         OTHERS

                 
 POST COITAL CONTRACEPTIVE

DRUGS

Dose

Pregnancy rate (%)
Levonorgestrel

O.75 MG STAT AND AFTER 12 HOURS
0-1
Ethinyl oestrodiol 30ug + Norgestrel 0.25 mg
2 TAB  STAT AND 2 AFTER 12 HOURS
0-2
Mifepristone
100 MG SINGLE DOSE

0-0.6
Copper IUDs
Insertion within 5 days
0-0.1

Levonorgestrel 0.75 MG ,two doses given at 12 hours intervals , is very successful and without any side effects .

No fetal adverse effects has been observed when there is failure of emergency contraception

Mode of action

·         Ovulation is either prevented or delayed when the drug is taken in the         beginning of the cycle
·         Fertilization is interfered
·         Implantation is prevented as the endometrium is rendered unfavorable.
·         Interferes  with the function of corpus luteum or may causes luteolysis.


Fig 1.4.b PostCoaital Contraceptions

Draw backs: 

Nausea and vomiting are much more intense with oestrogen use

Copper IUD: 

Introduction of copper IUD within a maximum period of 5 days can prevent conception following accidental unprotected exposure .this prevent implantation.

Anti progesterone: 

Anti progesterone binds competitively to progesterone receptors and nullifies the effects of endogenous progesterones.

PERMANENT METHODS    

The operation done on male is vasectomy and that on the female is tubal                    
occlusion, or tubectomy

VASECTOMY
Advantages:

1) The operation can be done as an outdoor procedure
2) Failure rate is minimal – 0.15 percent and there is a fair chance of success of reversal anastomosis operation (50%)

Female : TUBECTOMY
Puerperal:- 24-48 hours after delivery
Interval: 3 months after delivery. It is done after periods

Concurrent: 

done along with termination of pregnancy
Open—pomeroy’s method failure rate .1-.3%
Lap—rings  failure rate-.2--.6% 

        
Best infertility treatment in Chennai

Fig 1.15 Vasectomy 

Contraceptive prescription should be on individual basis. In an individual , Method may vary according to her phase of reproductive life .Teenage girls, Older women should also be protected.